Optical microscopes are an important tool in the fields of biology, medicine, and pharmacy. When biological work is directed towards sub-cellular structures, there is an ever increasing demand that optical microscopes have ultra-high resolution and real-time in vivo imaging. LCOS devices are highly flexible and may be integrated with other optical microscopy technology to meet the two requirements, above. Endoscopy minimises the harm done when observing the internal organs of the body. Increasingly miniaturized endoscopy tools has become an important direction for development. For example, a single multi-mode fiber could be used for both lighting and imaging to achieve the miniaturisation goal. This approach introduces image distortion due to the multi-mode fiber, but this problem can be resolved. LCoS can correct the distorted image by using optical phase conjugation. Optical coherence tomography is an optical imaging technique based on the principles of the Michelson interferometer. By employing a light source with low coherent length, the desired spatial resolution may be achieved. There are two effects generated when a spatial light modulator is integrated into optical coherence tomography. The first is to load a specific phase pattern on the SLM directly, allowing elimination of theAxicon (and the associated axial movement of focus) which is used to transform Gaussian beams to Bessel beams (desirable because Bessel beams have larger depth of focus than Gaussian beams). The second effect achievable by the use of LCoS is to improve the lateral resolution by employing aberration correction during ophthalmic OCT imaging. This technique is known as the adaptive optics – optical coherence tomography (AO-OCT). LCoS technology is widely applicable in the bio-medical field. The above examples show that it brings benefits and enables techniques that are not easily available by standard optical approaches.
Bio-Medical jdcUser 2018-01-04T15:23:06+00:00
What are the potential applications of LCoS technology for bio-medical technology?